Endocrine Abstracts

Thyroid hormone resistance is an inherited disorder with an incidence of about 1 in 50 000 live births. It is characterised by reduced response to the hormone at tissue level. Though many cases have been reported and there is growing awareness of the rare condition, there are reports of many patients being wrongly diagnosed as Graves disease and therefore undergoing various inappropriate treatments. We report the case of a 7-year-old boy who was referred to our service with ab...

Introduction: Neonatal thyroid screening commenced in the UK in 1981. The TSH cut off point cut off point has changed from 80 mu/l to 25 mu/l over the period for early detection and referral. From April 2006 in the West midland this has dropped to 20 mu/l as upper level and 10 mu/l as lower level.Method: Retrospective audit was undertaken in our hospital on babies referred with an abnormal Guthrie test for a period of 13 years from April 1996 to April 20...

Introduction: Microalbuminuria is the first of sign of incipient nephropathy and other micro vascular complications in the diabetic population. Up to 30% of the paediatric diabetic population are at risk of developing microalbuminuria by the age of 20. NICE 2006 recommends microalbuminuria screening from 12 years of age in children with type 1 diabetes however there is no guidance on specimen collection, test methodology or treatment regime. The definition of microalbuminuria ...